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LDL calculator (Friedewald and Sampson)

Most laboratories report LDL as a value calculated from the lipid panel. Here you can check it yourself and compare two formulas. You need total cholesterol, HDL and triglycerides.

mg/dL
mg/dL

Calculations run in your browser. We do not send or store anything.

Result

Fill in the fields to see the result.

How we calculate it

Friedewald (1972): LDL = total cholesterol − HDL − TG ÷ 5 (in mg/dL; in mmol/L the divisor is 2.2). Sampson (2020, NIH equation): LDL = TC ÷ 0.948 − HDL ÷ 0.971 − (TG ÷ 8.56 + TG × non-HDL ÷ 2,140 − TG² ÷ 16,100) − 9.44 (mg/dL).

Non-HDL cholesterol is total cholesterol minus HDL. It includes all atherogenic particles.

Limitations

  • The results are calculated, not directly measured. They may differ from the value reported by a laboratory that uses its own method.
  • Target LDL values depend on overall cardiovascular risk (e.g. the 2019 ESC/EAS guidelines) and are set by a doctor, so we do not label the result here as good or bad.
  • If familial hypercholesterolemia or elevated Lp(a) is suspected, a lipid panel alone is not enough: it is worth testing ApoB and Lp(a).

Sources