Weight Loss
Evidence-based weight loss — energy balance, satiety hormones and the most common dietary mistakes.
4.5Adaptive Thermogenesis
A drop in resting energy expenditure beyond what body-mass loss alone would predict — the mechanism explaining why weight loss naturally slows over time, even with a maintained calorie deficit.
4.6Leptin and Ghrelin
Two opposing hormones that regulate hunger and satiety — understanding how they work explains why losing weight is physiologically harder than a simple calorie-balance model suggests.
4.5NEAT (Non-Exercise Activity Thermogenesis)
All the energy burned on everyday movement unrelated to formal exercise — fidgeting, standing, gesturing — can differ by as much as 2000 calories a day between individuals, despite no difference in the number of planned workouts.
4.6Obesity
A chronic disease linked to excess body fat — and its relationship with mortality, mapped in the largest available meta-analysis covering over 10 million participants, has the shape of a curve, not a straight line.