VitMode

Hairy Bracket (Trametes hirsuta)

A common bracket fungus closely related to turkey tail, valued in biotechnology as a laccase producer. No clinical trials in humans and no presence on the supplement market.

MNMichał NowakReviewed by dr Piotr ZielińskiUpdated: June 10, 2026
Early-stage evidence
3.6

Number of studies

2

Safety

Moderate

Table of contents

TL;DR

A common bracket fungus closely related to turkey tail, valued in biotechnology as a laccase producer. No clinical trials in humans and no presence on the supplement market.

  • No studies in humans — available data is limited to in vitro tests of fruiting-body extracts and studies on laccase enzymes
Latin nameTrametes hirsuta
FamilyPolyporaceae (bracket fungi)
Active compoundsLaccases (enzymes), polyphenolic compounds
FormNot applicable — no commercial product exists
Level of evidencePreliminary/hypothesis — isolated in vitro and molecular studies
InteractionsNone described
StatusCommon in Poland; no dietary-supplement status; industrially valued as a laccase producer

Understand

Overview

Hairy bracket (Trametes hirsuta) is one of the most common bracket fungi in Poland, closely related to turkey tail. The fruiting bodies are semicircular, with a densely haired surface in shades of gray. It grows mainly as a saprotroph on dead deciduous wood.

Unlike turkey tail, Trametes hirsuta hasn't seen comparable human research and is not traded as a dietary supplement. It does, however, draw interest from biotechnologists as an efficient laccase producer — enzymes used for wastewater decolorization and bioremediation.

Given the current state of knowledge, hairy bracket won't "help" anyone as a supplement — because it simply isn't one. The only real target audience is biotechnologists working on enzymatic lignin breakdown and wastewater decolorization — for them, the species is a valuable source of laccases. For people looking for immune support through supplementation, it makes far more sense to reach for the well-studied relative, turkey tail, rather than this species.

Where it's found

Hairy bracket is one of the most common bracket fungi in Poland and worldwide, growing as a saprotroph on dead and decaying deciduous wood. Densely haired, grayish fruiting bodies appear year-round.

Mechanism of action

There's no established mechanism of action in the context of human health — research focuses on enzymes (laccase) that catalyze lignin breakdown. A few studies on fruiting-body extracts suggest the presence of compounds with antioxidant activity.

The laccase gene family of the Trametes hirsuta strain includes at least five identified genes, whose expression is induced by copper ions (Cu2+) — laccase, as a multicopper oxidase enzyme, requires copper as a catalytic cofactor for electron transfer during phenol oxidation. Separately from this enzymatic system, a study on selenium-enriched mycelium showed distinct antioxidant and cytostatic activity of the extracts.

1

Laccase gene expression induced by copper ions

The mycelium carries a family of at least five genes encoding laccase, whose transcription increases under the influence of copper ions.

2

Catalytic oxidation of lignin

Laccases catalyze the oxidation of phenolic and non-phenolic lignin components — used in bioremediation.

3

Antioxidant and cytostatic activity of extracts

Extracts from selenium-enriched mycelium showed antioxidant and cytotoxic activity in vitro, with no mechanistic link to the laccases.

Evidence: early-stage — based on 2 studies in this database.

Benefits

No studies in humans — available data is limited to in vitro tests of fruiting-body extracts and studies on laccase enzymes

Forms & variants

Hairy Bracket (Trametes hirsuta) comes in several forms that differ in bioavailability and use case — the form you pick genuinely matters for how effective the supplementation is.

Wild fruiting body on deciduous wood

The only form in which the species is found.

Best for: Mycological observation

Practice

Frequently asked questions

No — they're closely related but distinct species. Unlike turkey tail, it has no clinical research or drug status behind it.

Dosage & timing

Typical dose

Not established. Trametes hirsuta is not sold as a dietary supplement

Form

Not applicable

This entry is informational/mycological in nature, not a supplementation recommendation.

Best times to take it

  • Not applicable

Safety

Side effects & contraindications

Possible side effects

No safety data for use in humans

Contraindications

Not applicable — no registered products or any clinical data exist

Interactions

No interactions described

Is it worth taking?

Who it's for

  • No studies in humans — available data is limited to in vitro tests of fruiting-body extracts and studies on laccase enzymes

Not for

  • Not applicable — no registered products or any clinical data exist

Evidence

Worth knowing

Laccases from Trametes hirsuta are among the most intensively studied enzymes in environmental biotechnology.

The dense, felt-like hairs on the cap are the simplest way to distinguish it from turkey tail.

Studies

Molecular analysis identified a family of five laccase genes in a strain of Trametes hirsuta, whose transcription was regulated by copper ions.

Vasina D.V. et al., Biochimie, 2015

Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential

Early-stage evidence

Milovanovic I, Stanojkovic T, Stajic M, Brceskic I, Knezevic A, Cilerdzic J, Vukojevic J · Current Pharmaceutical Biotechnology · 2015

An in vitro study on selenium-enriched mycelium showed antioxidant activity and cytotoxicity against cancer cell lines.

View study

The Trametes hirsuta 072 laccase multigene family: Genes identification and transcriptional analysis

Research hypothesis

Vasina DV, et al. · Biochimie · 2015

A molecular study identified five laccase genes and described their regulation by copper ions — an enzymology study, not related to health.

View study

Sources & bibliography

Citations are illustrative for this demo version and require full bibliographic verification by the editorial team before production publication.

Compare with similar entries

About the authors of this entry

MN

Author

Michał Nowak

Clinical Dietitian

Michał specializes in metabolic nutrition, intermittent fasting and sports supplementation.

61 publications on this site

PZ

Medical review

dr Piotr Zieliński

Endocrinologist

Piotr reviews content on hormones, metabolic health and supplement pharmacology.

131 publications on this site

Published: March 14, 2025Updated: June 10, 2026

Related entries

Wachlarzowate, pręgowane owocniki wrośniaka różnobarwnego na drewnie4.5

Turkey Tail

The mushroom behind PSK and PSP — the only fungal polysaccharides registered in Japan as drugs supporting chemotherapy. Among the most solid clinical evidence of any functional mushroom, but this is NOT a standalone cancer therapy.

GrzybyModerate evidence
Grzyby naskalne rosnące na powalonej kłodzie3.9

Downy Bracket (Trametes pubescens)

A rarer relative of turkey tail, listed on Poland's red list of threatened fungi. It has a handful of laboratory studies and one animal study on a fruiting-body extract behind it, but zero clinical trials in humans.

GrzybyEarly-stage evidence
Grzyby naskalne na wilgotnej korze drzewa3.5

Ochre Bracket (Trametes ochracea)

A species nearly identical to turkey tail, often mistaken for it in the field. It has a single laboratory study on a fruiting-body extract behind it — no clinical trials whatsoever.

GrzybyEarly-stage evidence
Złociste grzyby naskalne oświetlone słońcem na kłodzie3.8

Birch Mazegill (Lenzites betulina)

A mushroom that looks like a turkey tail bracket but has true gills instead of pores underneath its cap. A handful of real laboratory studies (anticancer and antioxidant, in vitro), zero clinical studies in humans.

GrzybyEarly-stage evidence
Białe grzyby rosnące na pniu drzewa w lesie4.4

Lion's Mane

A functional mushroom studied for its effect on nerve growth factor (NGF) and cognitive function — human evidence is still preliminary.

GrzybyEarly-stage evidence
Świeże grzyby shiitake na targu4.3

Shiitake

A culinary-functional mushroom rich in lentinan and beta-glucans, studied clinically for immune modulation and lipid profile — one of the best-researched functional mushrooms on the market.

GrzybyModerate evidence
Zbiór suszonych grzybów o różnorodnych fakturach4.3

Tremella (Snow Fungus)

A jelly-like mushroom trendy in cosmetics as a 'vegan alternative to hyaluronic acid' — real clinical trials in humans, however, mostly involve oral supplementation and endpoints other than skin hydration.

GrzybyEarly-stage evidence
Faktura kory starego drzewa4.3

Antrodia camphorata (Niu Chang Zhi)

A mushroom endemic to Taiwan, growing exclusively on an endangered camphor tree, traditionally used for the liver — one of the few RCTs in humans shows a promising, if modest, improvement in liver enzymes.

GrzybyModerate evidence

Comments (2)

  • KW

    Kasia W. 2 weeks ago

    Very clearly explained, especially the interactions section — I hadn't seen it laid out this well anywhere else.

  • MT

    Marek T. a month ago

    Are you planning to update this with the newest study from this year? I saw an interesting meta-analysis.