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Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
Add to comparison (2/4)
| Category | TRT | TRT |
| Evidence strength | Strong evidence | Moderate evidence |
| Evidence Score | 5/5 | 3/5 |
| User rating | 4.6 (54) | 4.7 (58) |
| Typical dose | Usually 25–100 mg of testosterone daily, depending on the preparation's concentration (most often 1% or 1.62%) and the number of pumps or sachets used — the dose is set individually and adjusted based on follow-up blood tests 1–2 weeks after each change. | There's no single universal dose — it's chosen individually to achieve a testosterone concentration in the mid-to-upper reference range for healthy young men |
| Form | Transdermal gel in a metered-dose pump, single-use sachets, or a solution for underarm application with its own applicator — the exact form, concentration, and approved application sites depend on the specific registered preparation, so always follow that product's package insert. | Intramuscular/subcutaneous injections (every 1–2 weeks), transdermal gels and creams (daily), less commonly patches or subcutaneous implants |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | Steady-state testosterone concentration in skin and blood is reached after about 2 days of regular, daily use (Wang et al., 2000), but subjective improvement in energy, mood, and libido usually appears only after 3–6 weeks of consistent therapy — similar to other TRT delivery forms. | Libido and sexual function: 3–6 weeks. Muscle mass and strength: 3–6 months with concurrent training. Bone density: 12+ months. Mood, energy, and cognitive function: inconsistent effect, practically indistinguishable from placebo in many patients. |
| Who it's for | People who've already decided on testosterone gel and are looking for detailed instructions on correct use | Men with at least two confirmed, morning testosterone results below the laboratory reference range |