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Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
Add to comparison (2/4)
| Category | TRT | TRT |
| Evidence strength | Strong evidence | Strong evidence |
| Evidence Score | 5/5 | 5/5 |
| User rating | 4.6 (54) | 4.7 (52) |
| Typical dose | Usually 25–100 mg of testosterone daily, depending on the preparation's concentration (most often 1% or 1.62%) and the number of pumps or sachets used — the dose is set individually and adjusted based on follow-up blood tests 1–2 weeks after each change. | Not applicable — this piece describes the full diagnostic pathway preceding TRT, not a drug dosing schedule |
| Form | Transdermal gel in a metered-dose pump, single-use sachets, or a solution for underarm application with its own applicator — the exact form, concentration, and approved application sites depend on the specific registered preparation, so always follow that product's package insert. | Blood tests: total testosterone (2x morning), free testosterone, SHBG, LH, FSH, prolactin, estradiol, complete blood count with hematocrit, PSA, lipid panel, fasting glucose or HbA1c, liver function tests, TSH; plus a digital rectal exam and an ADAM/AMS symptom questionnaire |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | Steady-state testosterone concentration in skin and blood is reached after about 2 days of regular, daily use (Wang et al., 2000), but subjective improvement in energy, mood, and libido usually appears only after 3–6 weeks of consistent therapy — similar to other TRT delivery forms. | Not applicable — a diagnostic pathway preceding any possible start of therapy, usually taking several weeks. |
| Who it's for | People who've already decided on testosterone gel and are looking for detailed instructions on correct use | Men with symptoms suggesting testosterone deficiency (reduced libido, erectile dysfunction, chronic fatigue, loss of muscle mass) considering TRT |