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Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
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| Category | TRT | TRT |
| Evidence strength | Strong evidence | Moderate evidence |
| Evidence Score | 4/5 | 3/5 |
| User rating | 4.6 (58) | 4.7 (58) |
| Typical dose | Injections: usually 50–100 mg weekly or 100–200 mg every 2 weeks (cypionate/enanthate). Gel: an individual dose, usually 25–100 mg/day, easy to titrate every few weeks based on blood results. | There's no single universal dose — it's chosen individually to achieve a testosterone concentration in the mid-to-upper reference range for healthy young men |
| Form | Intramuscular or subcutaneous injections; transdermal gel applied daily to the skin of the upper arms, shoulders, or abdomen | Intramuscular/subcutaneous injections (every 1–2 weeks), transdermal gels and creams (daily), less commonly patches or subcutaneous implants |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | Hormone levels in the blood stabilize within a few weeks regardless of form; subjective improvement in energy and libido usually within 3–6 weeks. Differences in how stable well-being feels between forms typically show up only after several full dosing cycles (with injections) or after 2–4 weeks of daily routine (with gel). | Libido and sexual function: 3–6 weeks. Muscle mass and strength: 3–6 months with concurrent training. Bone density: 12+ months. Mood, energy, and cognitive function: inconsistent effect, practically indistinguishable from placebo in many patients. |
| Who it's for | People choosing a TRT form after a confirmed hypogonadism diagnosis and physician approval for therapy | Men with at least two confirmed, morning testosterone results below the laboratory reference range |