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Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
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| Category | TRT | TRT |
| Evidence strength | Strong evidence | Strong evidence |
| Evidence Score | 4/5 | 5/5 |
| User rating | 4.6 (58) | 4.7 (52) |
| Typical dose | Injections: usually 50–100 mg weekly or 100–200 mg every 2 weeks (cypionate/enanthate). Gel: an individual dose, usually 25–100 mg/day, easy to titrate every few weeks based on blood results. | Not applicable — this piece describes the full diagnostic pathway preceding TRT, not a drug dosing schedule |
| Form | Intramuscular or subcutaneous injections; transdermal gel applied daily to the skin of the upper arms, shoulders, or abdomen | Blood tests: total testosterone (2x morning), free testosterone, SHBG, LH, FSH, prolactin, estradiol, complete blood count with hematocrit, PSA, lipid panel, fasting glucose or HbA1c, liver function tests, TSH; plus a digital rectal exam and an ADAM/AMS symptom questionnaire |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | Hormone levels in the blood stabilize within a few weeks regardless of form; subjective improvement in energy and libido usually within 3–6 weeks. Differences in how stable well-being feels between forms typically show up only after several full dosing cycles (with injections) or after 2–4 weeks of daily routine (with gel). | Not applicable — a diagnostic pathway preceding any possible start of therapy, usually taking several weeks. |
| Who it's for | People choosing a TRT form after a confirmed hypogonadism diagnosis and physician approval for therapy | Men with symptoms suggesting testosterone deficiency (reduced libido, erectile dysfunction, chronic fatigue, loss of muscle mass) considering TRT |