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Supplement comparison tool

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CategoryTRTTRT
Evidence strengthStrong evidenceStrong evidence
Evidence Score5/55/5
User rating4.7 (102)4.7 (52)
Typical doseNot applicable — this entry describes a safety protocol, not therapy dosingNot applicable — this piece describes the full diagnostic pathway preceding TRT, not a drug dosing schedule
FormMonitoring: complete blood count with hematocrit every 3–6 months in the first year, PSA and digital rectal exam before starting and periodically thereafter, lipid panel once a yearBlood tests: total testosterone (2x morning), free testosterone, SHBG, LH, FSH, prolactin, estradiol, complete blood count with hematocrit, PSA, lipid panel, fasting glucose or HbA1c, liver function tests, TSH; plus a digital rectal exam and an ADAM/AMS symptom questionnaire
Average price
Monthly cost
Time to effectsNot applicable — monitoring is an ongoing process that continues throughout the entire course of therapy.Not applicable — a diagnostic pathway preceding any possible start of therapy, usually taking several weeks.
Who it's forAll patients starting or continuing TRTMen with symptoms suggesting testosterone deficiency (reduced libido, erectile dysfunction, chronic fatigue, loss of muscle mass) considering TRT