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Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
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| Category | TRT | TRT |
| Evidence strength | Strong evidence | Strong evidence |
| Evidence Score | 4/5 | 5/5 |
| User rating | 4.4 (87) | 4.7 (102) |
| Typical dose | Injections: usually 50–100 mg weekly or 100–200 mg every 2 weeks (cypionate/enanthate ester); gels: dose set individually based on blood test results | Not applicable — this entry describes a safety protocol, not therapy dosing |
| Form | Intramuscular/subcutaneous injections, transdermal gels and creams, less often patches | Monitoring: complete blood count with hematocrit every 3–6 months in the first year, PSA and digital rectal exam before starting and periodically thereafter, lipid panel once a year |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | Blood hormone levels stabilize after several weeks of starting therapy, regardless of form; subjective improvement in energy and libido usually appears within 3–6 weeks. | Not applicable — monitoring is an ongoing process that continues throughout the entire course of therapy. |
| Who it's for | Men with confirmed hypogonadism qualifying for TRT under the supervision of an endocrinologist or andrologist | All patients starting or continuing TRT |