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Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
Add to comparison (2/4)
| Category | TRT | TRT |
| Evidence strength | Strong evidence | Strong evidence |
| Evidence Score | 5/5 | 5/5 |
| User rating | 4.6 (58) | 4.7 (52) |
| Typical dose | Not applicable in the sense of drug dosing — what matters here is choosing an injection schedule that minimizes peak concentrations (e.g. more frequent, smaller doses instead of infrequent, large ones) as part of managing erythrocytosis risk. | Not applicable — this piece describes the full diagnostic pathway preceding TRT, not a drug dosing schedule |
| Form | A blood count assessing hematocrit and hemoglobin — done before starting TRT (baseline value), then periodically throughout therapy. | Blood tests: total testosterone (2x morning), free testosterone, SHBG, LH, FSH, prolactin, estradiol, complete blood count with hematocrit, PSA, lipid panel, fasting glucose or HbA1c, liver function tests, TSH; plus a digital rectal exam and an ADAM/AMS symptom questionnaire |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | The first measurable rises in hematocrit typically appear after several weeks to a few months of therapy; full stabilization at the new, higher equilibrium value most often occurs between month 3 and month 12 of treatment, absent any intervention. | Not applicable — a diagnostic pathway preceding any possible start of therapy, usually taking several weeks. |
| Who it's for | Men starting TRT who want to understand why blood count monitoring is a mandatory part of therapy, not a formality | Men with symptoms suggesting testosterone deficiency (reduced libido, erectile dysfunction, chronic fatigue, loss of muscle mass) considering TRT |