Tool
Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
Add to comparison (2/4)
| Category | TRT | TRT |
| Evidence strength | Moderate evidence | Strong evidence |
| Evidence Score | 3/5 | 5/5 |
| User rating | 4.6 (57) | 4.7 (52) |
| Typical dose | Cypionate/enanthate: most often 50–100 mg weekly, 100–150 mg every 10–14 days, or 25–50 mg twice a week at the same total weekly dose. Undecanoate: 750–1000 mg every 10–14 weeks after a loading-dose phase (a separate schedule — see our entry on delivery forms). | Not applicable — this piece describes the full diagnostic pathway preceding TRT, not a drug dosing schedule |
| Form | Intramuscular injections (usually the gluteal muscle or thigh) or subcutaneous (abdomen, thigh) — the choice of route and frequency depends on the preparation, patient preference, and tolerance. | Blood tests: total testosterone (2x morning), free testosterone, SHBG, LH, FSH, prolactin, estradiol, complete blood count with hematocrit, PSA, lipid panel, fasting glucose or HbA1c, liver function tests, TSH; plus a digital rectal exam and an ADAM/AMS symptom questionnaire |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | A new frequency schedule reaches its target, repeatable concentration profile usually after 3–5 half-lives of the ester used — for cypionate/enanthate, that's roughly 3–5 weeks of regular use. Subjectively assessing whether a given schedule actually flattened well-being swings usually requires observing at least 2–3 full dosing cycles on the new rhythm, not a single injection. | Not applicable — a diagnostic pathway preceding any possible start of therapy, usually taking several weeks. |
| Who it's for | Men just starting injectable TRT, setting their first dosing schedule with a doctor | Men with symptoms suggesting testosterone deficiency (reduced libido, erectile dysfunction, chronic fatigue, loss of muscle mass) considering TRT |