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CategoryTRTTRT
Evidence strengthModerate evidenceStrong evidence
Evidence Score4/55/5
User rating4.6 (52)4.7 (52)
Typical doseA morning blood draw (7:00–10:00); for an abnormal or borderline result — repeat on a separate day, also in the morning, before making any clinical decisionNot applicable — this piece describes the full diagnostic pathway preceding TRT, not a drug dosing schedule
FormTotal testosterone (serum) as the baseline test; for a borderline result, obesity, suspected SHBG disorders, or age above 40–50 — additionally free testosterone (calculated with the Vermeulen formula) and/or SHBGBlood tests: total testosterone (2x morning), free testosterone, SHBG, LH, FSH, prolactin, estradiol, complete blood count with hematocrit, PSA, lipid panel, fasting glucose or HbA1c, liver function tests, TSH; plus a digital rectal exam and an ADAM/AMS symptom questionnaire
Average price
Monthly cost
Time to effectsNot applicable — this piece is reference and diagnostic in nature, not a description of an intervention.Not applicable — a diagnostic pathway preceding any possible start of therapy, usually taking several weeks.
Who it's forMen who received a testosterone result and don't know how to interpret it in the context of their own ageMen with symptoms suggesting testosterone deficiency (reduced libido, erectile dysfunction, chronic fatigue, loss of muscle mass) considering TRT