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Supplement comparison tool

Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.

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CategoryTRTTRT
Evidence strengthModerate evidenceStrong evidence
Evidence Score3/55/5
User rating4.5 (58)4.7 (102)
Typical doseTypical doses are practically identical for both esters: 50–100 mg weekly, 100–200 mg every two weeks, or an equivalent dose split into more frequent, smaller injections — which we cover in more depth in our entry on testosterone injection frequency.Not applicable — this entry describes a safety protocol, not therapy dosing
FormAn oily solution for intramuscular or subcutaneous injection; concentration most often 200 mg/mL, though 100 mg/mL or 250 mg/mL occur depending on the manufacturer — it's the dose and concentration, not the ester itself, that determine the injection volume.Monitoring: complete blood count with hematocrit every 3–6 months in the first year, PSA and digital rectal exam before starting and periodically thereafter, lipid panel once a year
Average price
Monthly cost
Time to effectsNot applicable in a clinical sense — this is a comparison entry, not a description of an intervention. As for the time to reach a stable concentration after switching esters at the same dose and frequency, both preparations reach their target, repeatable profile in a similar timeframe, usually after 3–5 half-lives — practically indistinguishable between enanthate and cypionate.Not applicable — monitoring is an ongoing process that continues throughout the entire course of therapy.
Who it's forPatients on TRT wondering whether switching esters will change their well-being or therapy outcomesAll patients starting or continuing TRT