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Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
Add to comparison (2/4)
| Category | TRT | TRT |
| Evidence strength | Moderate evidence | Moderate evidence |
| Evidence Score | 3/5 | 3/5 |
| User rating | 4.5 (58) | 4.7 (58) |
| Typical dose | Typical doses are practically identical for both esters: 50–100 mg weekly, 100–200 mg every two weeks, or an equivalent dose split into more frequent, smaller injections — which we cover in more depth in our entry on testosterone injection frequency. | There's no single universal dose — it's chosen individually to achieve a testosterone concentration in the mid-to-upper reference range for healthy young men |
| Form | An oily solution for intramuscular or subcutaneous injection; concentration most often 200 mg/mL, though 100 mg/mL or 250 mg/mL occur depending on the manufacturer — it's the dose and concentration, not the ester itself, that determine the injection volume. | Intramuscular/subcutaneous injections (every 1–2 weeks), transdermal gels and creams (daily), less commonly patches or subcutaneous implants |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | Not applicable in a clinical sense — this is a comparison entry, not a description of an intervention. As for the time to reach a stable concentration after switching esters at the same dose and frequency, both preparations reach their target, repeatable profile in a similar timeframe, usually after 3–5 half-lives — practically indistinguishable between enanthate and cypionate. | Libido and sexual function: 3–6 weeks. Muscle mass and strength: 3–6 months with concurrent training. Bone density: 12+ months. Mood, energy, and cognitive function: inconsistent effect, practically indistinguishable from placebo in many patients. |
| Who it's for | Patients on TRT wondering whether switching esters will change their well-being or therapy outcomes | Men with at least two confirmed, morning testosterone results below the laboratory reference range |