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CategoryTRTTRT
Evidence strengthModerate evidenceModerate evidence
Evidence Score3/53/5
User rating4.4 (142)4.7 (58)
Typical doseStudies on gynecomastia used doses from 1 mg to 20 mg per day, with a clear dose-dependent protective effect — a specific regimen for a man outside the oncology context is set individually by the treating physicianThere's no single universal dose — it's chosen individually to achieve a testosterone concentration in the mid-to-upper reference range for healthy young men
FormOral tabletsIntramuscular/subcutaneous injections (every 1–2 weeks), transdermal gels and creams (daily), less commonly patches or subcutaneous implants
Average priceok. 20–40 zł za opakowanie (zależnie od dawki i liczby tabletek)
Monthly costok. 20–50 zł/miesiąc przy typowym schemacie, plus koszt wizyt i badań kontrolnych zlecanych przez lekarza
Time to effectsIn gynecomastia studies, the protective effect was assessed at 6 months (Fradet et al.) and at 48 weeks (Boccardo et al.) of regular use alongside the hormonal therapy creating the risk; for hormonal-axis support, time to effect is not as well characterized in dedicated studies as it is for clomiphene.Libido and sexual function: 3–6 weeks. Muscle mass and strength: 3–6 months with concurrent training. Bone density: 12+ months. Mood, energy, and cognitive function: inconsistent effect, practically indistinguishable from placebo in many patients.
Who it's forMen with gynecomastia related to hormonal therapy (including, occasionally, TRT) or an estrogen-androgen imbalance, under a physician's careMen with at least two confirmed, morning testosterone results below the laboratory reference range