Tool
Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
Add to comparison (2/4)
| Category | TRT | TRT |
| Evidence strength | Moderate evidence | Strong evidence |
| Evidence Score | 4/5 | 5/5 |
| User rating | 4.6 (52) | 4.7 (102) |
| Typical dose | SHBG is measured once from a venous blood sample, ideally together with total testosterone drawn in the morning (7:00–10:00), in the same draw | Not applicable — this entry describes a safety protocol, not therapy dosing |
| Form | Blood test: SHBG + total testosterone; for a borderline result, it's worth adding albumin to calculate free testosterone (Vermeulen formula) or ordering a direct free testosterone measurement by equilibrium dialysis | Monitoring: complete blood count with hematocrit every 3–6 months in the first year, PSA and digital rectal exam before starting and periodically thereafter, lipid panel once a year |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | Not applicable — this piece concerns interpreting a test result, not a therapeutic intervention. | Not applicable — monitoring is an ongoing process that continues throughout the entire course of therapy. |
| Who it's for | People with a borderline or ambiguous total testosterone result | All patients starting or continuing TRT |