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Supplement comparison tool
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| Category | Suplementy | Suplementy |
| Evidence strength | Strong evidence | Strong evidence |
| Evidence Score | 5/5 | 5/5 |
| User rating | 4.7 (189) | 4.9 (1042) |
| Typical dose | Deficiency prevention: RDA of about 14–16 mg/day; in dermatology trials on skin-cancer prevention: 500 mg twice daily (1000 mg/day) under medical supervision. Topically: cosmetics with 2–5% niacinamide, applied once or twice daily | 1000–4000 IU/day in healthy adults (target dose depends on baseline 25(OH)D level) |
| Form | Capsules/tablets taken orally; creams and serums with niacinamide applied topically to skin | Cholecalciferol (D3), preferably taken with fat or vitamin K2 |
| Average price | Doustnie: 15–35 zł za opakowanie starczające na miesiąc. Miejscowo: 20–80 zł za serum/krem z niacynamidem, zależnie od marki i koncentracji | 15–35 zł za opakowanie kropli/kapsułek na 2–3 miesiące |
| Monthly cost | ok. 15–80 zł/miesiąc, zależnie od formy i produktu | ok. 8–15 zł/miesiąc |
| Time to effects | Topically: sebum reduction can be measurable after just 2–4 weeks of regular use, effects on the barrier and hydration after 4–6 weeks, and visible reduction in discoloration usually after 8–12 weeks. Orally, in the context of skin-cancer prevention: effect was assessed in trials at 3, 6, 9 and 12 months of regular use. | 25(OH)D blood levels rise noticeably after 6–8 weeks of regular supplementation; subjective effects (energy, immunity) are sometimes reported earlier, but are harder to measure objectively. |
| Who it's for | People with combination or oily skin seeking to regulate excess sebum production | Practically the entire population of Poland during autumn and winter |