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CategoryLekiLeki
Evidence strengthModerate evidenceStrong evidence
Evidence Score3/55/5
User rating4.3 (58)4.5 (58)
Typical doseIn approved indications: usually 200 mg once daily in the morning (narcolepsy, sleep apnea) or about an hour before a night shift begins (shift-work disorder) — by prescription and under medical supervision onlyStart at 2.5 mg weekly, gradual escalation every 4 weeks to a maintenance dose of 5, 7.5, 10, 12.5, or a maximum of 15 mg weekly, depending on tolerance and treatment goal
FormOral tabletsSolution for subcutaneous injection in a single-use autoinjector (Mounjaro, Zepbound)
Average priceLek na receptę — cena i refundacja zależą od wskazania, zwykle 60–150 zł za opakowanie bez refundacjiok. 1000–1600 zł za opakowanie miesięczne, zależnie od dawki i apteki
Monthly costok. 60–150 zł/miesiąc przy codziennym stosowaniu bez refundacjiok. 1000–1600 zł/miesiąc
Time to effectsThe wake-promoting effect usually appears within 1–2 hours of taking a dose and lasts most of the day due to its long half-life (about 12–15 hours).Reduced appetite is sometimes noticeable within the first few weeks, but meaningful, measurable weight loss develops gradually over several months, and the full effect assessed in SURMOUNT-1 was measured after 72 weeks (about 1.5 years) of regular treatment.
Who it's forPatients with a confirmed narcolepsy diagnosis, qualified by a neurologist or sleep medicine specialistPeople with type 2 diabetes with inadequate glycemic control on other oral medications