Tool
Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
Add to comparison (2/4)
| Category | TRT | TRT |
| Evidence strength | Strong evidence | Moderate evidence |
| Evidence Score | 5/5 | 3/5 |
| User rating | 4.7 (62) | 4.7 (58) |
| Typical dose | Not applicable to drug dosing — what matters here is the numerical hematocrit value on a blood count and how it relates to the thresholds: <50% (normal), 50–54% (vigilance), ≥54% (intervention). | There's no single universal dose — it's chosen individually to achieve a testosterone concentration in the mid-to-upper reference range for healthy young men |
| Form | Complete blood count with hematocrit (Hct) and hemoglobin (Hb) — a standard venous blood draw, ideally done well hydrated and at a similar time of day across follow-ups for comparable results. | Intramuscular/subcutaneous injections (every 1–2 weeks), transdermal gels and creams (daily), less commonly patches or subcutaneous implants |
| Average price | — | — |
| Monthly cost | — | — |
| Time to effects | The thresholds described in this entry concern interpreting a result at a given moment, not an effect building up over time — the typical time for hematocrit to stabilize after starting or modifying therapy runs from a few weeks to about 3 months. | Libido and sexual function: 3–6 weeks. Muscle mass and strength: 3–6 months with concurrent training. Bone density: 12+ months. Mood, energy, and cognitive function: inconsistent effect, practically indistinguishable from placebo in many patients. |
| Who it's for | Men on TRT who just got a blood count result and want to know where their hematocrit falls on the scale and whether it calls for a response | Men with at least two confirmed, morning testosterone results below the laboratory reference range |