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CategoryTRTTRT
Evidence strengthStrong evidenceStrong evidence
Evidence Score5/55/5
User rating4.7 (62)4.7 (52)
Typical doseNot applicable to drug dosing — what matters here is the numerical hematocrit value on a blood count and how it relates to the thresholds: <50% (normal), 50–54% (vigilance), ≥54% (intervention).Not applicable — this piece describes the full diagnostic pathway preceding TRT, not a drug dosing schedule
FormComplete blood count with hematocrit (Hct) and hemoglobin (Hb) — a standard venous blood draw, ideally done well hydrated and at a similar time of day across follow-ups for comparable results.Blood tests: total testosterone (2x morning), free testosterone, SHBG, LH, FSH, prolactin, estradiol, complete blood count with hematocrit, PSA, lipid panel, fasting glucose or HbA1c, liver function tests, TSH; plus a digital rectal exam and an ADAM/AMS symptom questionnaire
Average price
Monthly cost
Time to effectsThe thresholds described in this entry concern interpreting a result at a given moment, not an effect building up over time — the typical time for hematocrit to stabilize after starting or modifying therapy runs from a few weeks to about 3 months.Not applicable — a diagnostic pathway preceding any possible start of therapy, usually taking several weeks.
Who it's forMen on TRT who just got a blood count result and want to know where their hematocrit falls on the scale and whether it calls for a responseMen with symptoms suggesting testosterone deficiency (reduced libido, erectile dysfunction, chronic fatigue, loss of muscle mass) considering TRT