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Supplement comparison tool

Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.

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CategoryTRTTRT
Evidence strengthStrong evidenceStrong evidence
Evidence Score5/55/5
User rating4.7 (52)4.7 (102)
Typical doseNot applicable — this piece describes the full diagnostic pathway preceding TRT, not a drug dosing scheduleNot applicable — this entry describes a safety protocol, not therapy dosing
FormBlood tests: total testosterone (2x morning), free testosterone, SHBG, LH, FSH, prolactin, estradiol, complete blood count with hematocrit, PSA, lipid panel, fasting glucose or HbA1c, liver function tests, TSH; plus a digital rectal exam and an ADAM/AMS symptom questionnaireMonitoring: complete blood count with hematocrit every 3–6 months in the first year, PSA and digital rectal exam before starting and periodically thereafter, lipid panel once a year
Average price
Monthly cost
Time to effectsNot applicable — a diagnostic pathway preceding any possible start of therapy, usually taking several weeks.Not applicable — monitoring is an ongoing process that continues throughout the entire course of therapy.
Who it's forMen with symptoms suggesting testosterone deficiency (reduced libido, erectile dysfunction, chronic fatigue, loss of muscle mass) considering TRTAll patients starting or continuing TRT