Tool
Supplement comparison tool
Pick up to 4 knowledge base entries and compare their dosage, price, evidence strength and ratings side by side — you can save or share a link to your selection.
Add to comparison (2/4)
| Category | TRT | TRT |
| Evidence strength | Moderate evidence | Moderate evidence |
| Evidence Score | 3/5 | 3/5 |
| User rating | 4.3 (203) | 4.7 (58) |
| Typical dose | The cited RCTs in older men typically used low doses, ranging from a fraction of a milligram up to 1 mg, several times a week or daily depending on the trial protocol. There is no single, universally validated regimen for every man on TRT — the dose should be set individually by a physician based on baseline and follow-up estradiol levels. | There's no single universal dose — it's chosen individually to achieve a testosterone concentration in the mid-to-upper reference range for healthy young men |
| Form | Oral tablets | Intramuscular/subcutaneous injections (every 1–2 weeks), transdermal gels and creams (daily), less commonly patches or subcutaneous implants |
| Average price | ok. 20–50 zł za opakowanie, zależnie od dawki i liczby tabletek | — |
| Monthly cost | ok. 10–40 zł/miesiąc przy typowych, niskich dawkach off-label | — |
| Time to effects | Changes in blood estradiol and testosterone are usually visible within a few weeks (in the cited Leder et al. RCT, hormonal effects were already assessed after a short treatment period). Improvement in subjective symptoms, if it occurs at all, is far less predictable and did not differ significantly from placebo in two independent RCTs. | Libido and sexual function: 3–6 weeks. Muscle mass and strength: 3–6 months with concurrent training. Bone density: 12+ months. Mood, energy, and cognitive function: inconsistent effect, practically indistinguishable from placebo in many patients. |
| Who it's for | Men on TRT with laboratory-confirmed, repeated, symptomatic estradiol excess, under the care of a physician experienced in managing TRT | Men with at least two confirmed, morning testosterone results below the laboratory reference range |