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	Anastrozole on TRT	What Tests Are Needed Before TRT? The Complete Pre-Treatment Testing List
Category	TRT	TRT
Evidence strength	Moderate evidence	Strong evidence
Evidence Score	3/5	5/5
User rating	4.3 (203)	4.7 (52)
Typical dose	The cited RCTs in older men typically used low doses, ranging from a fraction of a milligram up to 1 mg, several times a week or daily depending on the trial protocol. There is no single, universally validated regimen for every man on TRT — the dose should be set individually by a physician based on baseline and follow-up estradiol levels.	Not applicable — this piece describes the full diagnostic pathway preceding TRT, not a drug dosing schedule
Form	Oral tablets	Blood tests: total testosterone (2x morning), free testosterone, SHBG, LH, FSH, prolactin, estradiol, complete blood count with hematocrit, PSA, lipid panel, fasting glucose or HbA1c, liver function tests, TSH; plus a digital rectal exam and an ADAM/AMS symptom questionnaire
Average price	ok. 20–50 zł za opakowanie, zależnie od dawki i liczby tabletek	—
Monthly cost	ok. 10–40 zł/miesiąc przy typowych, niskich dawkach off-label	—
Time to effects	Changes in blood estradiol and testosterone are usually visible within a few weeks (in the cited Leder et al. RCT, hormonal effects were already assessed after a short treatment period). Improvement in subjective symptoms, if it occurs at all, is far less predictable and did not differ significantly from placebo in two independent RCTs.	Not applicable — a diagnostic pathway preceding any possible start of therapy, usually taking several weeks.
Who it's for	Men on TRT with laboratory-confirmed, repeated, symptomatic estradiol excess, under the care of a physician experienced in managing TRT	Men with symptoms suggesting testosterone deficiency (reduced libido, erectile dysfunction, chronic fatigue, loss of muscle mass) considering TRT