VitMode

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Supplement comparison tool

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CategoryLekiLeki
Evidence strengthStrong evidenceStrong evidence
Evidence Score4/54/5
User rating4.3 (58)4.5 (76)
Typical doseUsually started at 25 mg once daily, titrated gradually up to 50–100 mg three times daily with the first bite of each main meal — gradual titration significantly reduces the severity of gastrointestinal side effectsDetermined individually by a doctor, usually 500–2000 mg daily in divided doses, with meals
FormOral tablets taken right before or with the first bite of a mealOral tablets, including extended-release (XR) forms that reduce gastrointestinal discomfort
Average price——
Monthly cost——
Time to effectsThe effect on post-meal glycemia is visible from essentially the first correctly timed dose (within hours), while improvement in longer-term markers like HbA1c usually takes 8–12 weeks of regular use at the target dose.Lowering of glycemia is usually visible within days to weeks of starting therapy and reaching the target dose.
Who it's forPeople with type 2 diabetes whose main problem is post-meal glycemia, assessed by a doctorPeople with type 2 diabetes or prediabetes, qualified by a doctor